Due to the visible decline of freshwater turtles in Amazon, the Brazilian government created numerous conservation projects since the 70s, to protect these species. Studies on females’ microhabitat nesting choice provided essential information for the success of such management and conservation projects. However, little is known about the female choice at a broader level on the Amazon Basin. Nest annual mortality vary from zero to 100% depending on the location and species. This annual variation in nest mortality is a complex phenomenon, which requires long-term monitoring of nesting sites to be understood. The complexity of the climatic and geomorphological changes in nesting beaches over time should be taken into account and we should develop dynamic strategies to mitigate both natural and anthropogenic negative effects. We use remote sensing and spatial analyses, and nests success rates data for areas monitored by the Project “RAN Amazon Turtles” in the last 30-40 years to access the level of vulnerability of Amazon Turtle’s nests to climate change . This study has the potential to become a powerful tool for nest success prediction, monitoring and prioritization, which can be extended to the entire Amazon Basin.